Aspergillosis

Lung fungal infection in immunocompromised patients. Opportunistic mold causing invasive pulmonary disease and ABPA.

Key facts

CauseFungus
SpreadAirborne (Spores)
Incubation1–14 days
VaccineNo
TreatmentAntifungals (Voriconazole)

Did you know?

In Allergic Bronchopulmonary Aspergillosis, steroids reduce inflammation but suppress antifungal immunity, allowing continued fungal growth despite symptom improvement. Iron chelation can help by starving Aspergillus, but excessive chelation impairs the already steroid-weakened neutrophil response. This creates a treatment paradox where both anti-inflammatory therapy and iron restriction can simultaneously help and harm the patient.

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