HPV
STI causing warts and cervical cancer, prevented by the Gardasil vaccine. Papillomavirus with koilocytes; oncogenic types 16/18 drive cervical dysplasia.
Key facts
| Cause | Virus |
|---|---|
| Spread | Direct contact |
| Incubation | 30–240 days |
| Vaccine | Yes |
| Treatment | No treatment for the virus; lesions treated with cryotherapy/podophyllotoxin |
Did you know?
The most famous cell line in all of biology — HeLa, the first immortal human cells, used in millions of experiments including the polio vaccine — came from Henrietta Lacks's cervical cancer, which was driven by HPV-18. The viral DNA had integrated right next to the c-myc oncogene, and the E6/E7 proteins switched telomerase back on, which is a large part of why those cells never stop dividing to this day.
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