Kuru

'Laughing death' of the Fore people of Papua New Guinea, spread through funeral cannibalism. Progressive cerebellar ataxia and tremor.

Key facts

CausePrion
SpreadRitual cannibalism
Incubation1640–18250 days
VaccineNo
TreatmentNo available cure after symptoms appear

Did you know?

Mortuary feasts stopped in the late 1950s, but cases kept appearing for nearly 50 years, and the last patients died in the 2000s. This gave the longest human prion incubation periods ever documented and showed that prion diseases can stay silent for half a century.

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