Typhoid
Bacterial infection from contaminated food/water causing weeks of high fever and abdominal pain. Rose spots, step-ladder fever pattern.
Key facts
| Cause | Bacteria |
|---|---|
| Spread | Fecal-oral |
| Incubation | 6–30 days |
| Vaccine | Yes |
| Treatment | Antibiotics (Ceftriaxone/Azithromycin) |
Did you know?
S. typhi specifically damages intestinal brush border lactase enzymes through direct enzymatic cleavage. This creates permanent lactose intolerance in up to 30% of survivors. In patients with sickle cell disease, S. typhi has a unique tropism for bone marrow in the femur and humerus.
Next: Whooping Cough
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