Typhoid

Bacterial infection from contaminated food/water causing weeks of high fever and abdominal pain. Rose spots, step-ladder fever pattern.

Key facts

CauseBacteria
SpreadFecal-oral
Incubation6–30 days
VaccineYes
TreatmentAntibiotics (Ceftriaxone/Azithromycin)

Did you know?

S. typhi specifically damages intestinal brush border lactase enzymes through direct enzymatic cleavage. This creates permanent lactose intolerance in up to 30% of survivors. In patients with sickle cell disease, S. typhi has a unique tropism for bone marrow in the femur and humerus.

Next: Whooping Cough

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